Assay
Age
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Western blot
13.5 DPC
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Rb1 RB transcriptional corepressor 1 (Synonyms: pRb, Rb, Rb-1, retinoblastoma 1) | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:131845 Ciemerych MA, Yu Q, Szczepanska K, Sicinski P, CDK4 activity in mouse embryos expressing a single D-type cyclin. Int J Dev Biol. 2008;52(2-3):299-305 |
1 | J:345472 Lana-Elola E, Aoidi R, Llorian M, Gibbins D, Buechsenschuetz C, Bussi C, Flynn H, Gilmore T, Watson-Scales S, Haugsten Hansen M, Hayward D, Song OR, Brault V, Herault Y, Deau E, Meijer L, Snijders AP, Gutierrez MG, Fisher EMC, Tybulewicz VLJ, Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Sci Transl Med. 2024 Jan 24;16(731):eadd6883 |
1 | J:51060 LeCouter JE, Kablar B, Hardy WR, Ying C, Megeney LA, May LL, Rudnicki MA, Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Mol Cell Biol. 1998 Dec;18(12):7455-65 |
1 | J:113043 Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K, Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 1994 Sep 1;8(17):2008-21 |
1* | J:82897 Leezer JL, Hackmiller RC, Greene RM, Pisano MM, Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development. Orthod Craniofac Res. 2003 Feb;6(1):32-47 |
1 | J:201041 Park DS, Tompkins RO, Liu F, Zhang J, Phoon CK, Zavadil J, Fishman GI, Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system. Biol Open. 2013;2(9):968-78 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1* | J:233705 Zhao H, Wang H, Bauzon F, Lu Z, Fu H, Cui J, Zhu L, Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis. J Biol Chem. 2016 May 6;291(19):10201-9 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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